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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '376998e38109382934c5418af08645b873193afa106aaba360f1a12a0598544a' 
  AND token = 'BiSUtFjg+AZqIdccufoe235aoVGQ1hMxMuiEfeKpP7U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}