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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10004d97616927a286284a08e1e76fad8deeb3b7fa5d2e52ffed929b7ec155cd' 
  AND token = 'HMlObtHKqEPvNr20taYeJe/WCUuCghmPuLWIJPQo1iM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}