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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a537d1a5005c7b95d4d9ea2a3a0e019bf58a4cf4d224147bde0ae692b621579' 
  AND token = '3QI36D7bOSZ6fxWehwOhNqrZBLVCEPXT19srZBAb/7Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}