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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed29eeb0997e818829590d555bc5d9b719284fc2cdb188b486ca19ae4e8fc233' 
  AND token = 'grwBAQQ5edxp7jZ8lNB0DicnZ5/4Yj1dxbhZcR4s8hQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}