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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '782a4275c10cc07ce07e713c8edfff3b9f56c8f54fe2c9ff6764dacd2bec404a' 
  AND token = 'XeNHpAHYT0Mt57z+xIZknePqT39WZLHIrsApi3K1DkQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}