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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de46ffc5f4ee502cc5762086b32d021d830216c2a1ae6308bcfb2ac41e4aefa8' 
  AND token = 'llT61JvrHFqUTYn2oN3A+8xGct5eJ3i/c0oLi+3QLlM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}