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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1bfe0eb37b1a05eb259d5438ae81080798744f8aa15755e4c1be74dfff39428a' 
  AND token = 'q5X/mX084OIS832xWD+qboQj5Rq3XwklDTVxj923nys=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}