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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10f7eebdec51ced575a9100393dd705d7fa19c974e3a767d1e5a28e9aab0918b' 
  AND token = '6E2Qzx9C+pqqNnbVg4SBXHenlh9tQ+onAZ/+Wt8nRfk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}