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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '789c21425cffa11f16899888f8b81c591c57d987aff64f73d2daa10c80ebc434' 
  AND token = 'XbqZO4JR6Mj42K4ZOc6iLPRCUxVu5c6IrTt504rF40E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}