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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64acf75e255e9f4d2435ab776d415d51e8e77475873b347f4e720b29a5e52126' 
  AND token = '+MlG2T22453IvPOD4qmvlp8QJp2yc0UjigrU1qA1rPc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}