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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '676d90e50ccb6909e4e7b4e5608151327b415006c5fe1ab5e1f8a502d4331367' 
  AND token = '4k0RQ9EgATpLvkvod7tr8SwOKSQGrjtYACo4NAQipoY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}