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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e83226c7e9381bcb981560eaa863a8ed70f97323fa9b612cc069f7dc08ecb66d' 
  AND token = 'HInCxaTnVvbZNPywDwxr2O2OA3zK7yMG5VCAUZ3ja3M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}