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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4cadcb955c4bace4dc7bf387d29ec1997db20f22df9b2519bfdc73d2cd8bd9b4' 
  AND token = 'ifdn+IFQ2N/6zawBgrgAT6C/TRlY33SAcxIO8dkOLq0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}