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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae350685a987951d4fc124cd36e4a8148378de3838a855dd074a46dbd46a3a86' 
  AND token = 'YMQmmt5WB8xAoh5onzWdvtTjC1G0SOV7m9+twkEjZ8U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}