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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '646ee7d3cf8e83303876990dda2e4d29b64360dcba76b1ab89f32619d31b8746' 
  AND token = 'DdSpOYd23YWe+lxdwbGjAM6WOdG04nlNfvscTEIMjaA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}