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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea3e6ee8aac62b0977bc2a2950245e8492f7f264e3222f670d40503e0a4e813c' 
  AND token = 'oDWFwTh6RBiGl2beb+XmqwCiInAQATJFBr9Gxtb7qjs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}