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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5dcd834defe145aba3bc5f4258de973b328cf72eff1a3a54497df4f8c389b9c2' 
  AND token = '2uU1RT6yLy/FZ0kszuZFpamZUvxwSwaOr3yHvZYSySU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}