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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a36a6174be5ec6b21807e5d6bf0d145779ea49f1c075b34e83f605b4da8cc52' 
  AND token = 'KUfq9V5Z0Wi3wpepH2MeWo5vH/dTkEgo3RuM2aREpxI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}