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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22813bd609516a3ad9f4704e06f194a309b443e849da2a4a25db0e362a6e6747' 
  AND token = 'oK0mud5LV2LjDvLU83uAWHIi40TIzC5GMHLhFb8OgqA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}