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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51630519c1939a72eace19146429bb586195537c465ff9a0571c233b0f81b91e' 
  AND token = '50TE/k9PUez4J47ct39Ce7OVj05ODVR/n/lW79xArcc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}