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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2049ed5ace1ee9e0e96558b9643cb69ef6fad70ba0e912f6129c62fe89898509' 
  AND token = '5DgC7ezn6TZxccLY2bZMqp/SPaxkDvVr4abrY/aifaE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}