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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc0365498e338a692884c7c122d289e8380a6b71f50bda18a07dccd9e78e0b33' 
  AND token = '9DiPCyW43UjEf1RZ9rQXKCv6Q1rVk7AlG1oz7PUP+eM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}