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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c122d0d8bc40f8afd59974edaf53b612dfe861399305f5c16cdeea1793f62d2' 
  AND token = 'Yu2FxZYpnH7rNHPcXataLZ9LV4WGjuQIIMHfDnCaAr8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}