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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2abfb013f3b1670f7c954953719290a0da7d8b668f7571a06a56b90591f60634' 
  AND token = 'F8IeOjK2zMeRidS8DKO4y3gQPhMK1p+DJW3GGn9RF0U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}