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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c5241ce0cf7d0704eb2362a0db11787217238763ed09f81176c7610d26a0cbf' 
  AND token = 'AoCb+gryHZ8f4xJEQDQVWKO46OkW9jBVjsy/zz2O4U0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}