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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de5435c37553867c0c0905303f57e21f781778bec4e718cf4410273cf3844a25' 
  AND token = 'qohGVXGqv+ntAiGtf9bHhR532k1soD9Dk1FMkO0W8n4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}