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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f8dd375dafa4ce9632760c3574810832c149fdcd7eee09d3b1ee998f7424ed5' 
  AND token = 'e9ndDihp1EjIetT0sS4Lst0HEDW027W1YqShO0xXKmw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}