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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41a0d127d54ca88c68ad04a45b3a3b144b9e8a1a13258803db0818f9d72c8b6c' 
  AND token = 'zWysBTMQsyuxI6HUQk9tC0KMSA3v6XrrJAbEuIHBs2Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}