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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea48cd5172e0a836a369e6301c79d625d96b6ee8c0a1335d9b1958b67790cff3' 
  AND token = '/rpIOpKfaSfdisObGBBTT4Vp0PDYWyqxvSxoU7jvTfY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}