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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '392c1ff27441a56b3997f92af0a9dab25562999ad72ab93bf2d74bc798cff227' 
  AND token = 'd3v9gyeKDYT3COItve1+7vRvbaX74PDOOWGQIm05+TQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}