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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '440df330885e0b1e1c671f75dd141c9fb98389bbc98863bd7e58599b9cd1c81a' 
  AND token = 'HB777fH9SZ0FNFt8vOSCVIJ6Nf+IQ9Ei1ZK459v74TA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}