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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b992d362c892f2d7238f67bf2c2dd831b6d0aa22d5fdede56f31d50c2979fc1' 
  AND token = 'v+UlCB1ZrZSVQHOkHrAeltcSJz+O4CVuc4tcBA9bAAQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}