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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '85b75924e774d5879fbfb3330acb7a54e7bc53c709ecd623f726607342e8a9b0' 
  AND token = 'fNYvRhO6zAXxlXy17V7ZZ5PTRBAZwHAk26pWplf2ICI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}