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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b5e238ef581d7364b075f1b57e0b72dfba6cdf700fc922071c0f03cd2052dba' 
  AND token = 'e2tj6bb+KfPmmf6RTOXeLwmuVIdYrTrQ622mKF/0C/Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}