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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '70d8a46430d5e79d62f18f5182a53c9a3e4eed2ff25350df092d12c3a79d2740' 
  AND token = 'eZs+FHpedie4BHe7SfDTGZmBz2hiCuu8k8U9CxJrbeY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}