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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed0e6137cc43630b3c1be89b91a78c0b8d236e61c3dff4ec896ccdc5428094f3' 
  AND token = 'w2tQULRQ3HHkbxlKwu+M6XdBfHJZdjKUSQYzgaeTi6U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}