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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c21a04a881955e1a2cc177aff3d2df246e0ed8cbe2c5a2424c990fcef6070f2a' 
  AND token = 'VrD9hjwXT//M6GlK8uu3Fe/hFIlvD8dX12lLPbVBHNA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}