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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1b021e84783854be1b1c98e6075d5029466a19061950d2befdd288b5e899c4d' 
  AND token = 'N3zpjCApIa8RxCAsin3koM6o08dWvWNep+GZuHi60YA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}