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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e5450bdecb1f2b83f37b03af088dca3830f98ce072c98368d3571a03c5c1d52' 
  AND token = '+Hucrd0g7tIMXLgpS5GYwxPmIRDM5V0KhN196rzEzn8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}