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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2350ad9e15d77eeecd8e7d78307edc0b720b75b3ec1d8f0eb6e7b7af5c14814' 
  AND token = 'vfgXD4HGQ9kIS3UCI1Arlqqe3bhdRxAF2r+hT5FG1i8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}