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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14444257a3310ea24a57c2ec588bfe7516fdcb906edaf598c8231b8023dd3c1a' 
  AND token = 'UrrPuaBbdK+6khKF6TRyS41WTvK2rx01a7aRxXGZg1s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}