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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b30378f4734c9aaa5d836260c06c5b11b62c11cd3c2b49546bd1db8343c105e9' 
  AND token = 'pIqTseUxgMxpUTEYemUNYGUQTL3kxGkf6BbfawFNcr0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}