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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10427f73acd509d744021cbd7c422fe0bc6e7ba1b78e83517ef1788edfe10ac8' 
  AND token = 'cgAvvTVA3tY0VokktbX6CGnTKDGMHctn76aIZM6qXn4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}