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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '271ab619b2da9bdbd8de321696b8116955e9034690191f20b14d75b939bc9c05' 
  AND token = '1mA+ZIoA4zuF2GAeIELGk1JbpB9UH44PCgZ66WDA7eQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}