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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e529a919cd239d9befc5cabf8cabca0d047f2afe737180ce1c3e553d22df1f5f' 
  AND token = 'KrKDX99N3wd+ydBNh7vZ+9EcsKbWh23C4aeW2fq/GD8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}