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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4d9642e045587b7ca003516ff0ba48b675b4ddea2b99bb6365859e7e61e063e' 
  AND token = '12vp9V+NU+YmKYwJD2cos3P0ZesWZiVd4asMtCNakA4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}