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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a52ec56490ca8c7e9df4f3f82ae938311bb98b748aafad402b8eb99250ea51c1' 
  AND token = 'ESUE6EwrLKit9HdqhkGYcfNcTrsIXUMrj/7R/7gohZQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}