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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '406d02e40d7affea7861d62b52d1a5bb57eab87d396a8057311d0e9d5bef0d06' 
  AND token = 'MFUNplcBnWow9aO6eBc+MOYcvjCDDHRaOa8e1/dx0WY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}