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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af3de205d3d6a79d69676b2c49f688280f382c648b8f2d69356e4196b3396e71' 
  AND token = 'k3JxnxNsmBa7ICu5AINCSC3Rjpw3K6AoeaVyCxZXgu8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}