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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '492d7a20ff9d184d7f739fd86f430d02f1ed1e00991b15c8fc2340ecd1ed2ac6' 
  AND token = '2I0JrK8tVssoSqNFZbncmZvtckgeykiyVD1Xg3ovWuk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}